Diagnóstico premotor de la enfermedad de Parkinson

Autores/as

  • Pablo Venegas F. Hospital Clínico Universidad de Chile. Departamento de Neurología y Neurocirugía. Unidad de Trastornos del Movimiento

Resumen

Parkinson is a neurodegenerative disease that compromises brain nuclei in an ordered pattern. Only when Sustancia Nigra compromise becomes severe, motor signs are noticed. This occurs late in Parkinson course, so there is a long time period before in which no motor signs are evident. This is “premotor phase” of Parkinson disease. To make diagnosis early in premotor phase, would allow beginning a potential treatment that modify disease course. In this article we discuss clinical picture of premotor phase of Parkinson disease, local reality about ancillary tests to improve diagnosis sensibility of it and we suggest treatment approach.

Palabras clave:

Enfermedad de Parkinson/diagnóstico, Enfermedad de Parkinson/prevención & control, Trastornos Parkinsonianos/diagnóstico