Malignant gliomas represent 80% of primary malignant central nervous system tumors. It generally presents with headache, epilepsy, cognitive change, dysphasia, or progressive hemiparesia. Current standard treatment for malignant glioma includes: surgical resection or biopsy, radiation therapy and/or chemotherapy. The prognosis of malignant gliomas is still dismal despite aggressive treatment attempts. Understanding the molecular pathogenesis of glioma may lead to a rational development of new therapies. This review summarizes the diagnosis and management of these tumors in adults.
Sinning O., M. . (2009). Gliomas de alto grado en adultos. Revista Hospital Clínico Universidad De Chile, 20(3), pp. 215–20. https://doi.org/10.5354/2735-7996.2009.76575
